A candidate gene is a gene that is suspected of being involved in a diseases or specific trait. When we talk about candidate genes association studies, we actually mean that we want to analyze some mutations in the candidate genes that we have selected for our study. So first, how can we choose candidate genes for a genetic study? There are many different ways to do so. Read More »
Many diseases have a genetic basis and researchers often focus in identifying the genes that are implicated in these diseases, in order to be able to detect it as early possible, to prevent if from developing and also to investigate possible treatments. The candidate gene approach has been widely used to try to identify genes but what is it and how does it work exactly? Read More »
The Hardy-Weinberg principle, which states that a polymorphism genotype frequencies in a population remain constant, is commonly used in population genetic studies. Download this simple Hardy-Weinberg Equilibrium Calculator Excel file and use it to calculate if the genotypes frequencies you obtained in your population are in Hardy-Weinberg Equilibrium (HWE). You only need to replace the values in the pink boxes by your own genotypes frequencies and if the p-value obtained in the yellow box is higher than 0.05, you will know that your data does respect the equilibrium and might thus be considered as a good sample for your study!
Hardy Weinberg Equilibrium Calculator
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